Median survival time after video-assisted thoracic surgery (VATS) talc pleurodesis for MPE is approximately 10.5 months, with a range from a few days to over 5 years in selected cases.

Other studies report median survival after pleurodesis ranging from 3 to 12 months, commonly around 10 to 12 months

Presence of extrathoracic metastasis and duration of disease over 12 months also correlate with increased mortality risk, although these may vary in significance.

One-year survival rates after VATS talc pleurodesis are about 44%, with 3- and 5-year survival rates of roughly 10% and 2%, respectively.